Package: scOntoMatch Type: Package Title: Aligning Ontology Annotation Across Single Cell Datasets with 'scOntoMatch' Version: 0.1.1 Authors@R: c(person(given = "Yuyao", family = "Song", email = "ysong@ebi.ac.uk", role = c("aut", "cre", "ctb")), person(given = "Irene", family = "Papatheodorou", email = "irenep@ebi.ac.uk", role = c("aut", "ths"))) Maintainer: Yuyao Song Description: Unequal granularity of cell type annotation makes it difficult to compare scRNA-seq datasets at scale. Leveraging the ontology system for defining cell type hierarchy, 'scOntoMatch' aims to align cell type annotations to make them comparable across studies. The alignment involves two core steps: first is to trim the cell type tree within each dataset so each cell type does not have descendants, and then map cell type labels cross-studies by direct matching and mapping descendants to ancestors. Various functions for plotting cell type trees and manipulating ontology terms are also provided. In the Single Cell Expression Atlas hosted at EBI, a compendium of datasets with curated ontology labels are great inputs to this package. Imports: ontologyIndex, ontologyPlot, purrr URL: https://github.com/Papatheodorou-Group/scOntoMatch BugReports: https://github.com/Papatheodorou-Group/scOntoMatch/issues License: MIT + file LICENSE Encoding: UTF-8 RoxygenNote: 7.2.3 Depends: R(>= 3.5) Suggests: knitr, devtools, SeuratObject VignetteBuilder: knitr Config/pak/sysreqs: zlib1g-dev Repository: https://papatheodorou-group.r-universe.dev Date/Publication: 2023-10-27 12:36:33 UTC RemoteUrl: https://github.com/papatheodorou-group/scontomatch RemoteRef: HEAD RemoteSha: 93799368f8fd3a569130368f239cc4c053ddbaeb NeedsCompilation: no Packaged: 2026-06-09 07:09:47 UTC; root Author: Yuyao Song [aut, cre, ctb], Irene Papatheodorou [aut, ths]